Sunday, July 21, 2013

Quantifying Expert Judgment for a Bayesian Analysis

In my view, one of the merits of a Bayesian analysis is the opportunity to develop a prior probability model using expert elicitation to express scientific knowledge. Expert elicitation involves a carefully-crafted interview process with a subject-area expert to translate an expert’s knowledge into a prior probability for a Bayesian analysis. For the elicitation, a specific strategy is recommended that involves: motivating, structuring, conditioning, encoding, and verifying:

·   Motivating (establishing rapport): This involves making sure that the expert has a comfortable understanding of the process.  This includes explaining the nature of problem and analysis, giving the expert context on how his or her judgments will be used, discussing the general methodology of a probabilistic assessment, explaining heuristics expert can use, and identifying any potential motivational biases.

·   Structuring (defining uncertain quantities): Once the expert is oriented as to the general what, how, and why, the next step is to clearly define the specific questions about which the expert will be providing judgment.  During this step, it is important to define variables of interest unambiguously and identify variable units as well as possible ranges of values. Variables can be disaggregated into more elementary variables, if necessary, or combined into summary variables, as appropriate.

·   Conditioning (thinking about all evidence): After the specific values to be elicited are chosen, the expert should then be prompted to think about all of his or her relevant expert knowledge concerning the variables and relationships of interest.  This knowledge could include data, theoretical models, analogies with similar systems, or other sources of understanding.  The expert should be encouraged to think from different perspectives and draw on as much information as possible in order to overcome potential biases related to consideration of limited scope.  For example, the elicitor can ask the expert to invent scenarios for extreme outcomes and ask the expert to explain how these different outcomes could occur.
·   Encoding  (quantifying expert judgment): After proper preparation in previous steps, this step comprises the actual elicitation.  Probabilistic information can be elicited according to many different proposed protocols, for example, the elicitor can fix the probability and directly elicit the variable value or conduct an indirect reference lottery.
·   Verifying (checking the answer): Finally, after all desired probabilities are encoded, the elicitor should test the expert answers given to see if they correctly capture the expert’s opinion.  This can be done by rephrasing an expert’s answer in another way to see if the expert still agrees with the assessment.  If the expert does not confirm the answer, the elicitor may need to repeat conditioning and encoding steps.
As an example, Reckhow (1988) used expert judgment to improve a model of fish population response to acid deposition in lakes when the knowledge of an expert is elicited and formally incorporated into the model using Bayes Theorem. In Reckhow’s study, an expert (Dr. Joan Baker) in fish response to acidification was interviewed to elicit a prior probability for the model parameters. The model was a logistic regression model with the form
where p(Presence) is the probability of species presence, b represents the model parameters, and x represents the predictor variables (pH and calcium).
Since with a statistical model, scientific experts are more likely to think in terms of the variables (pH, calcium, and species presence/absence) rather than in terms of the model parameters, a predictive distribution elicitation ap­proach was used to de­termine the prior probabilities. For this procedure, the expert was given a set of predictor variables and then asked to give her estimate of the median response. A frequency perspective was thought to facilitate response; thus a typical question was: “Given 100 lakes that have supported brook trout populations in the past, and if all 100 lakes have pH = 5.6 and calcium concentration = 130 ueq/L, what number do you now expect continue to support the brook trout population?” This question was repeat­ed 20 times with a variety of pH-calcium pairs to yield 20 predicted responses. Twenty was chosen to provide some re­dundancy to improve characterization of the prior yet not burden the expert with time-consuming questions. The pH-­calcium pairs were not randomly selected but rather were chosen to resemble the sample data matrix.
The expected response provided by Dr. Baker does not pro­vide a crucial measure of error. Thus, it was assumed that the errors in the conditional response were approximately nor­mally distributed, and additional questions were posed to Dr. Baker to determine fractiles of the predictive distribution, con­ditional on pH and calcium. A typical question was: “For pH = 5.1 and calcium = 90 ueq/L, you estimated that 55 lakes supported brook trout populations. If the odds are 3:1 that the number of lakes (of 100 total lakes) supporting brook trout is greater than a particular value, what is that value?” This question yields the 25th%, and other similar questions provide other percentiles. These fractiles were assessed for six conditional y [p(Presence)] distributions, producing six estimates for stan­dard error that are conditional on an assumed known un­derlying variance (estimated from the data). A thorough description of this probability elicitation and the complete Bayesian analysis can be found in Reckhow (1988).  

Kashuba, Roxolana, McMahon, Gerard, Cuffney, T.F., Qian, Song, Reckhow, Kenneth, Gerritsen, Jeroen, and Davies, Susan, 2012, Linking urbanization to the Biological Condition Gradient (BCG) for stream ecosystems in the Northeastern United States using a Bayesian network approach: U.S. Geological Survey Scientific Investigations Report 2012–5030, 48 p. (http://pubs.usgs.gov/sir/2012/5030/.)


Reckhow, K.H. 1988.  A Comparison of Robust Bayes and Classical Estimators for Regional Lake Models of Fish Response to Acidification. Water Resources Research. 24:1061-1068.

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